| Title: | Dietary Vitamin E Intake Is Associated With a Reduced Risk of Developing Digestive Diseases and Nonalcoholic Fatty Liver Disease |
| Journal: | The American Journal of Gastroenterology |
| Published: | 14 Mar 2022 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/35288522/ |
| DOI: | https://doi.org/10.14309/ajg.0000000000001726 |
| URL: | https://www.ncbi.nlm.nih.gov/pmc/articles/9177739 |
Publication 18691
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Abstract
INTRODUCTION: Vitamin E supplementation is recommended for the treatment of nonalcoholic fatty liver disease (NAFLD) for nondiabetic patients, but its preventative effects are unclear.</p>
METHODS: We assessed dietary vitamin E intake with disease phenotypes and evaluated vitamin E levels with the development of NAFLD.</p>
RESULTS: Data from >210,000 participants demonstrate that increased dietary vitamin E associates with reduced rates of several gastrointestinal diseases and reduced overall mortality. Diabetic and overweight subjects with increased vitamin E intake have fewer NAFLD diagnoses.</p>
DISCUSSION: Our findings reveal the relevance of vitamin E consumption for several gastrointestinal diseases and warrant further mechanistic and therapeutic investigations.</p>
5 Keywords
- Diet
- Humans
- Non-alcoholic Fatty Liver Disease
- Nutritional Status
- Vitamin E
8 Authors
- Eleonora Scorletti
- Kate Townsend Creasy
- Marijana Vujkovic
- Mara Vell
- Inuk Zandvakili
- Daniel J. Rader
- Kai Markus Schneider
- Carolin V. Schneider
1 Application
| Application ID | Title |
|---|---|
| 71300 | Elucidating host-environment interactions in gastrointestinal diseases |
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