| Title: | The Association of TyG Index with Morbidity and Mortality of Cardiovascular Diseases. |
| Lead Institution: | Shunde Hospital of Southern Medical University |
| Principal investigator: |
Application 356978
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About
Aims: The primary aim of this research is to determine if the TyG index, a measure based on blood triglyceride and glucose levels, can predict the risk of developing cardiovascular diseases (CVD). We want to find out if people with higher TyG index values are more likely to suffer from heart attacks, strokes, and other heart-related problems. Furthermore, we aim to identify the potentially effect of various risk factors in terms of lifestyle, diet, treatment, genetic susceptibility, plasma metabolites on the transition from healthy state to CVD and subsequently to related chronic multimorbidity. Scientific rationale: Cardiovascular diseases are major causes of illness and death worldwide. Current methods to predict who is at risk can be complex and expensive. The TyG index is a simple, inexpensive measure that might help identify high-risk individuals more easily. By validating this index, we hope to provide a tool that can be used widely to prevent CVD by identifying at-risk individuals early. Project duration: This project duration is estimated for 3 years. Public health impact: This research could significantly improve public health by: 1. Early Detection: Identifying individuals at high risk of cardiovascular diseases early on, allowing for timely interventions. 2. Cost-Effective Prevention: Providing a low-cost method for risk assessment, making it accessible for more people. 3. Improving Health Outcomes: Reducing the number of heart attacks, strokes, and related deaths by enabling early treatment and lifestyle changes. 4. Informing Healthcare Policies: Helping shape public health strategies and policies to better allocate resources for preventing cardiovascular diseases.1 Publication
| Pub ID | Title | Author(s) | Year | Journal |
|---|---|---|---|---|
| 18379 | Time to first cigarette after waking and incident heart failure: a dose-response analysis from the UK biobank | Jiahua Wen (+8) | 2026 | ESC Heart Failure |
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