| Title: | Cardiovascular-kidney-metabolic Syndrome and Geriatric Syndrome: Multidimensional Analyses of Health Risks in the Middle-Aged and Elderly Population |
| Lead Institution: | Wenzhou Medical University |
| Principal investigator: |
Application 292953
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About
Cardiovascular-kidney-metabolic (CKM) syndrome is a health disorder due to connections among heart disease, kidney disease, diabetes, and obesity, increasing the risk of development and progression of cardiovascular disease and leading to poor health outcomes. Geriatric syndromes!GS! are common conditions that affect older adults and can have a significant impact on quality of life, such as frailty, falls, cognitive impairment, and depression. People with CKM syndrome are often more likely to develop GS!and GS also promotes the progression of CKM syndrome. The aim of this research project is to investigate the interactions and effects of GS and CKM syndrome on each other. In addition, we will also investigate the risk and protective factors associated with both syndromes, including demographic, lifestyle, health, and genetic factors, and explore the underlying mechanisms that drive their progression over time. The project is expected to last three to four years, and the findings will have an important impact on public health. By finding the interaction between GS and CKM syndrome and identifying the factors that contribute to the development and progression of GS or CKM syndrome, this study will inform the development of targeted prevention and intervention strategies to improve health status and quality of life in middle-aged and older adults.1 Publication
| Pub ID | Title | Author(s) | Year | Journal |
|---|---|---|---|---|
| 18251 | Liver fibrosis biomarkers as a prognostic tool beyond the defining components in cardiovascular-kidney-metabolic syndrome | Zhenyang Cao (+7) | 2026 | American Journal of Preventive Cardiology |
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