| Title: | Age and gender adjusted low serum apolipoprotein A1, high C-reactive protein as predisposing biomarkers of SARS-CoV-2 infection. A large retrospective study using UK biobank. |
| Lead Institution: | Assistance Publique - Hôpitaux de Paris |
| Principal investigator: | Professor Thierry Poynard |
Application 79974
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About
The aim of this project is to validate a blood based risk stratification tool, combining existing and routinely available markers (apolipoprotein-a1, C-reactive protein) with age and gender that could be an additional diagnosis and prognosis tool for screening subjects at high-risk of SARS-Cov-2 infection (SI). The 2 biomarkers have a published role in the SARS-Cov-2 infection, with normal values depending on age and gender. A score combining the values of the 2 assays, corrected by age and gender, will be correlated to the risk of SI. The project will last 3 years. The public health impact could be major, helping the clinicians stratifying the patients according to this novel risk score.1 Publication
| Pub ID | Title | Author(s) | Year | Journal |
|---|---|---|---|---|
| 17240 | An Invisible Early Steatosis Phenotype Defined for a Large Population-Based Cohort | Thierry Poynard (+9) | 2025 | Biomedicines |
Enabling scientific discoveries that improve human health