| Title: | Gut-brain connections from magnetic resonance images |
| Lead Institution: | First Affiliated Hospital of Zhejiang University School of Medicine |
| Principal investigator: |
Application 176969
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About
Aims: This study aims to uncover the connection between gut and brain based on MRI Scientific rationale: Using multiorgan MRI and genetic data from subjects of UK biobank, we aimed to quantify interorgan connections between the gut and brain. We aim to analyze the distribution of substances in the brain and gut and study its effect on disease progression through the brain-gut axis. Project duration: Estimated duration of this project is expected to be 3 years. Public health impact: Our research project will help the study of disease mechanism and may provide a new target for treatment.4 Publications
| Pub ID | Title | Author(s) | Year | Journal |
|---|---|---|---|---|
| 19396 | A study of the protective association of hard water on ulcerative colitis and Crohn's disease: a cross-sectional and cohort study of 481,468 participants in the UK Biobank | Kexin Ye (+5) | 2025 | BMC Gastroenterology |
| 16591 | Healthy Plant-Based Diet Is Associated With a Reduced Risk of Inflammatory Bowel Disease: A Large-Scale Prospective Analysis | Zhenhe Jin (+7) | 2025 | Molecular Nutrition & Food Research |
| 19388 | Integrated Metabolic and Inflammatory Clustering Reveals Distinct Risk Profiles for Digestive Diseases | Zhenhe Jin (+10) | 2025 | Advanced Science |
| 15509 | Plasma Metabolite Profiles Linked to EAT-Lancet Diet and Risk of Inflammatory Bowel Disease: A Prospective Cohort Study From UK Biobank | Xiaohua Ye (+2) | 2025 | Molecular Nutrition & Food Research |
Enabling scientific discoveries that improve human health